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Medication Problems

  • NSAID or Non Steroidal Anti-Inflammatory Drug (EG Motrin, Aleve, Meloxicam) Use Before Rotator Cuff Surgery Increases Failures

    Although the general public is generally not aware of it, it is well established in the medical literature that NSAID drugs interfere with healing. For this reason in particular I never use them when I perform reparative surgery where they might compromise the surgical repair. This has been well shown in various animal studies but there have few studies in humans where it has been looked at. However in a new study from Norway the use of NSAIDs before surgery was correlated with a greater chance of failure afterward. This is quite significant in that the drug use did not have to be during the period of healing to impair healing later. The most common drugs in this class are Ibuprofen (motrin, advil), Naproxen (Aleve), and Aspirin over the counter and Diclofenac, Meloxicam and Celebrex by prescription.

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  • Cipro And Other Fluroquinolone Antibiotics Associated With Tendon Ruptures And Other Complications

    A few weeks ago I saw a 90 year old retired doctor, whose physician daughter brought him in, with one completely ruptured Achilles tendon and one partially ruptured. Usually these require significant trauma – which he did not have. What was the cause? In his case the tendon ruptures were the result of his having taken Cipro, a Fluoroquinolone antibiotic for an infection. In fact such tendon injuries, and other complications with use of these antibiotics are relatively common so that the FDA on 7/26/2016 wrote:

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  • Peri-Operative NSAIDs Use Found To Correlate With Increased Revision Rate After ACL Reconstruction

    A recent study from the US Naval Academy has shown that the use of NSAIDs (nonsteroidal anti-inflammatory drugs) such as advil, motrin, aleve, diclofenac and meloxicam around the time of surgery or afterward.

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  • Statins Drugs Can Cause Tendon Damage

    Statins drugs can cause tendon damage. A New study shows how it happens. Statins drugs to control cholesterol are heavily prescribed. However there have been many reports of serious side effects, including tendon damage or rupture.

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  • Long-Term Oral Bisphosphonate Therapy and Fractures in Older Women: The Women's Health Initiative

    Long term use of osteoporosis drugs linked to INCREASED risk of fractures

    Yet another study has appeared showing an increased risk of problems with bisphosphonate drugs for osteoporosis. Bisphosphonate drugs such as Fosamax and Boniva appear to show a slight reduction in fracture risk in osteoporotic patients in short term use. However prior studies have shown an increased risk of spontaneous femur fractures requiring surgery and also osteonecrosis of the jaw when used for five years. Now a new study from the West Coast has also shown that the risk of fractures actually goes up with use over 10 years compared to use for two years.

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  • American Academy Regenerative Medicine
  • American Academy and Board of Regenerative Medicine
  • American Orthopaedic Society for Sports Medicine
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  • Rush University Medical Center
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  • American Academy of Orthopaedic Surgeons
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