Knee / ACL Surgery

  • Dr. Prodromos ACL Blog August 2017

    It is well established that Non-Steroidal Anti-inflammatory Drugs (NSAIDs) such as ibuprofen (motrin, advil), naproxen (aleve), aspirin, celebrex, diclofenac, and meloxicam interfere with the healing of ligaments, bones, tendons and other connective tissue. For this reason Orthopaedic Surgeons are cautious in their use after reconstructive surgery and in other applications - although there are few clinical studies showing the effect of NSAIDs on outcomes. However, a recent paper entitled Predictors of Revision Surgery After Anterior Cruciate Ligament Reconstruction from the US Navy published in the American Journal of Sportsmedicine found a significant correlation with the use of NSAIDs and an increased rate of revision, i.e. failure, after ACL reconstruction. This held true for both so-called COX-1 NSAIDs, the vast majority available, and also COX-2 NSAIDs which include Celebrex and Meloxicam. The authors write “Increased odds of revision surgery among active-duty personnel were associated with the perioperative use of NSAIDs and COX-2 inhibitors.” This reinforces the conclusion found in one of the few other papers to look at this topic The effect of ketorolac on anteroposterior knee laxity after anterior cruciate ligament reconstruction. where it was found that “The use of ketorolac during bone-patellar tendon autograft ACL reconstruction was associated with increased AP laxity at 6 weeks postoperatively.”

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  • Dr Prodromos ACL Blog February 2016

    Anterior cruciate ligament reconstruction with a novel porcine xenograft: the initial Italian experience Anterior cruciate ligament reconstruction and service in the British Army Long-Term Examination of Bone Mineral Density in the Calcanei After Anterior Cruciate Ligament Reconstruction in Adolescents and Matched Adult Controls

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  • Dr Prodromos ACL blog September 2015

    PATELLAR TENDON GRAFTS FOUND TO HAVE INCREASING INCIDENCE OF KNEELING PAIN AFTER SURGERY ALLOGRAFTS FOUND TO HAVE THREE TIMES THE FAILURE RATE OF AUTOGRAFTS

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  • Dr Prodromos ACL blog July 2015

    Article 1 this month found mesenchymal stem cells in the stump of torn ACLs. This finding opens the way for possible technology to regrow ACLs in the laboratory by culturing these cells. While this technology would be many years away at best, this finding is an important first step. Article 2 measured the levels of

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  • Dr Prodromos ACL blog March 2015

    Each month there are roughly 50 – 75 new scientific journal articles in the world’s peer reviewed literature dealing with the human ACL which we collect and peruse. I will summarize the main point of those few that, in my opinion, say something genuinely new or particularly important in this monthly blog. ARTICLES

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